Ehlers-Danlos syndrome (EDS) is a group of inherited disorders that affect the connective tissue. Most individuals affected with EDS have soft, stretchy skin, hypermobile joints and bruise easily. EDS type VIIc, also known as EDS, dermatosparaxis type, is known for extremely fragile skin that sags and wrinkles. Children with EDS type VIIc will also have extra folds of skin that become more noticeable as they get older. They also have hypermobile joints that may delay motor skills such as sitting, standing or walking. Some affected individuals have short stature and some may have a slightly blue color to the whites of their eyes. Infants typically have a soft, outward bulging of the abdominal lining around the belly button, called a hernia. Some children have some characteristic facial features that include a small chin and puffy eyelids. Intellect is not affected by EDS type VIIc. Life expectancy is usually normal. There is no cure for EDS type VIIC but medical care and surveillance can help improve some symptoms and overall condition of life. EDS type VIIc is caused by pathogenic variants in the ADAMTS2 gene.