Congenital Amegakaryocytic Thrombocytopenia (CAMT) is an inherited bone marrow failure disorder that begins in infancy. In this disease, the blood producing cells in the bone marrow do not produce platelets, which are important for blood clotting, or megakaryocytes, which are responsible for producing platelets. This means the child's blood will not clot properly after bleeding. Over time, the bone marrow may stop making red blood cells and neutrophils. The symptoms for CAMT, such as bruising and bleeding, can be life threatening. Intellect is not affected by CAMT. Currently, the only treatment for CAMT is bone marrow transplantation. CAMT is caused by pathogenic variants in the MPL gene.