Wilson disease is an inherited disorder affecting copper metabolism, causing copper to build up in the body. The organs most affected are the liver, brain, and eyes. People with Wilson disease can develop liver disease, problems controlling movement, and psychiatric or behavioral problems. They will often a distinct eye anomaly, called Kayser-Fleischer rings, which are rings of copper in the cornea of the eye. These rings do not affect vision. Disease onset ranges from 3 to 50 years old. Lifelong treatment with copper chelating agents or zinc can reduce symptoms in some patients. With proper life-long surveillance and treatment, life expectancy is normal. Intelligence is not affected by Wilson Disease. Wilson disease is caused by pathogenic variants in the ATP7B gene.